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Pilot clinical studies and case reports describe nausea in 65% of subjects at doses above 0,5 mg (resolution 2-4 h post-injection), flushing in 55%, transient increases in blood pressure and tachycardia in 40-60% of subjects, with peak acute effects occurring 90-120 minutes post-dose

As the body adjusts to the medication, there might be temporary changes in taste preferences or cravings

Free (unbound) lipoic acid supplements may contain either R -lipoic acid or a 50:50 (racemic) mixture of R -lipoic acid and S -lipoic acid (see Supplements)

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